General Information

The histology material in the Molecules, Cells, and Tissues and Normal Body courses will be presented in a variety of ways, including lectures, laboratories (described in this Lab Manual), readings (lecture notes and textbook), and the Histology Time computer atlas that has been loaded on your computers.  The lectures and labs are the main methods used to present the material, whereas each student should select among the textbook, lecture notes, and Histology Time to find the style(s) that are most helpful for review.  Our purpose is not to overburden you with material, but rather to provide you with several opportunities to learn and understand the course information.  Notes for each lecture, as well as the PowerPoint lectures, are available on “Blue Docs”.

Our glass slides have been scanned and digitized in such a way as to permit analysis and viewing of the slides at very high resolution on your computer (“Virtual Microscopy”).  The webslides are delivered from a central server to your personal computer that acts as a digital microscope. To help you navigate these slides, we have put together this online laboratory manual which contains:

  1. directions for proper use of your virtual microscope
  2. links to the relevant slides for each lab session
  3. hints for slide study
  4. descriptions of all slides
  5. lab review material

There are several other excellent reference and study materials available for both the Molecules, Cells, and Tissues and the subsequent Normal Body course.  We recommend that you try each of the different resources listed below to find the one(s) most useful for you.

  • The recommended textbook is Histology: A Text and Atlas, 6th edition by Ross and Pawlina, although eariler editions are fine (the notes occasionally refer to a specific figure in the 6th Edition, but the equivalent figure is generally also in the other editions). Note, however, that purchasing a new copy will also give you electronic access to the text and atlas at http://thepoint.lww.com.  
  • Histology Time, a computer atlas with many excellent images and descriptions, has been loaded onto your computers.

If you do decide to purchase a textbook, is a good idea to bring this book to the laboratory sessions, as the images can be helpful in orienting you for examination of the VM slides.

 

Histology Content in the Molecules, Cells, and Tissues Course


A. Introduction and Objectives

In the Molecules, Cells, and Tissues course, we will cover the microscopic anatomy of the basic tissues that comprise the the human body, which are:

  • epithelial tissues
  • connective tissues, including blood, cartilage, and bone
  • muscle tissues
  • nerve tissues

Our main goal is to explain the basic concepts and principles that govern the basic structure and function of each tissue.  Microscopic Anatomy uses lectures and laboratory sessions, with the lectures designed to provide background knowledge about each tissue and to serve as introductions or previews for the labs.  In the labs, each student will be able to learn at his/her own pace and develop skills at solving structural problems by analyzing data directly obtained with light (virtual) microscopic observations.  By the end of this course each student should be able to recognize, describe, and differentiate basic tissue types, their extracellular components, and their consituent cells.


B. Molecules, Cells, and Tissues Histology Lecture and Lab Schedule

Date
Lecture Time
Topic
Lecturer
Lab Time
Wed 8/20
1:10-2:00
Introduction to the histology lab
McIntosh
--
Wed 8/20
--
Introductory Lab
Staff
2:10-4:00
Mon 8/25
Exam 1
         
Wed 9/3
11:10-12:00
Epithelium I
McIntosh
--
Thr 9/4
1:10-2:00
Epithelium II
McIntosh
--
Thr 9/4
--
Epithelium Lab
Staff
2:10-4:00
Fri 9/5
9:10-10:00
Connective Tissue I
Erickson
--
Fri 9/5
10:10-11:00
Connective Tissue II
Erickson
--
Fri 9/5
11:10-12:00
Blood
Perz-Edwards
--
Fri 9/5
--
Connective Tissue & Blood Lab
Staff
2:10-4:00
Mon 9/8
Exam 2
Mon 9/8
1:10-2:00
Cartilage
Erickson
--
Tue 9/9
9:10-10:00
Bone I
Erickson
--
Tue 9/9
10:10-11:00
Bone II
Erickson
--
Tue 9/9
--
Cartilage & Bone Lab
Staff
1:10-3:00
Thr 9/11
9:10-10:00
Cell Biology of the Nervous System I
Velkey
--
Thr 9/11
10:10-11:00
Cell Biology of the Nervous System II
Velkey
--
Thr 9/11
--
Nerve Tissue Lab
Staff
2:10-4:00
Fri 9/12
10:10-11:00
Skeletal and Smooth Muscle Histology
Carbrey
Tue 9/16
--
Muscle Tissue Lab and Final Review
Staff
1:10-4:00
Fri 9/19
Exam 3 and Lab Practical Exam


C. Histology Lab Instructors


Lab 1 (room 3051):  Dr. Tom McIntosh

Lab 2 (room 3052):  Dr. Mimi Jakoi 

Lab 3 (room 3053):  Dr. Joe Corless

Lab 4 (room 3054):  Dr. Steve Vigna

Lab 5 (room 3055):  Dr. Matt Velkey

Lab 6 (room 3056):  Dr. Jennifer Carbrey

D. Interim and Final Exams

As shown on the schedule, there will be three Molecules, Cells, and Tissues Exams that will contain multiple choice or matching type questions pertaining to the material covered in the lectures.  In addition there will be a Lab Practical Exam that will ask you to identify labeled tissues (e.g. "stratified, squamous non-keratinized epithelium") on virtual microscope slides, and justify your identification with a brief discussion of the key structural features.  The last lab session in the course (Muscle Tissue) includes extra time for review, during which time your lab instructor will detail the format of the exam and provide you with the opportunity to hone your skills at examining VM sections and identifying tissues and cells.

 

Histology Content in the Normal Body Course


A. Introduction and Objectives

In Normal Body we will cover the microscopic anatomy of the major organ systems of the human body.  Our main goal is to explain the basic concepts and principles that govern the structure of each organ.  You will analyze how the four major tissue types studied in Molecules, Cells, and Tissues (epithelium, connective tissue, muscle, and nerve) organize and integrate to form the organs.  Microscopic Anatomy uses lectures and laboratory sessions, with the lectures designed to serve as introductions or previews for the labs.  In the labs, each student will be able to learn at his/her own pace and develop skills at solving structural problems by analyzing data directly obtained with light (virtual) microscopic observations.  By the end of this course each student should be able to recognize, describe, and differentiate the major organs according to their cellular structure and tissue distribution.

Normal Body links structure with function.  The information in Microscopic Anatomy is closely correlated with the structural and functional concepts and principles that you will be learning in the Gross Anatomy and Physiology.  The Normal Body course has been designed so that, as closely as possible given the constraints imposed by gross anatomy dissections, the three disciplines will cover the same organ systems in the same time frame.  In particular, the course is scheduled so that the microscopic anatomy of a given organ system will be presented immediately before the physiology lectures on that organ.  In this way, the nomenclature and cellular structure of the organ system is learned before the biological mechanisms and processes. 


B. Normal Body Histology Lecture and Lab Schedule

Date
Lecture Time
Topic Lecturer
Lab Time
Mon., 9/22
9:10-10:00
Introduction McIntosh
--
Mon., 9/22
10:10-12:00
Skin Carbrey
--
Mon., 9/22
--
Skin Lab Staff
1:10–3:00
   
Fri., 9/26
9:10-10:00
Cardiovascular McIntosh
--
Fri., 9/26
--
Cardiovascular Lab Staff
10:10-12:00
   
Tues., 10/07
10:10-11:00
Respiratory McIntosh
--
Wed., 10/08
--
Respiratory Lab Staff
10:10-12:00
   
Wed., 10/15
11:10-12:00
Lymphatic System Jakoi
--
Thurs., 10/16
9:10-10:00
Lymphatic System  Jakoi
--
Thurs., 10/16
--
Lymphatic System Lab Staff
10:10-12:00
   
Tues., 10/21
10:10-11:00
GI Tract McIntosh
--
Wed., 10/22
--
GI Tract Lab (Esophagus/Stomach) Staff
1:10-4:00
Thurs., 10/23
10:10-11:00
GI Tract McIntosh
--
Thurs., 10/23
--
GI Tract Lab (Intestines)                    Staff
1:10-4:00
Fri., 10/24
--
Review Lab Staff
10:10-12:00
   
Mon., 10/27
9:10-11:00
MA Exam and Practical (Lectures and Labs from 9/22-10/24) 
Tues., 10/28
10:10-11:00
GI Glands Klingensmith
--
Tues., 10/28
11:10-12:00
GI Glands Klingensmith
--
Thurs., 10/30
--
GI Glands Lab Staff
1:10-3:00
   
Tues., 11/04
10:10-11:00
Urinary Jakoi
--
Tues., 11/04
11:10-12:00
Urinary Jakoi
--
Wed., 11/05
--
Urinary Lab Staff
10:10-12:00
   
Thurs., 11/13
9:10-10:00
Endocrine Glands Carbrey
--
Fri., 11/14
9:10-10:00
Endocrine Glands Carbrey
--
Fri., 11/14
--
Endocrine Glands Lab Staff
10:10-12:00
   
Mon., 12/01
9:10-10:30
Male Reproductive System McIntosh
--
Tues., 12/02
--
Male Reproductive Lab Staff
9:10-12:00
   
Wed., 12/03
10:10-11:00
Female Reproductive System Carbrey
--
Wed., 12/03
11:10-12:00
Female Reproductive System Carbrey
--
Thurs., 12/04
--
Female Reproductive Lab Staff
9:10-12:00
   
Thurs., 12/11
--
Review Lab Staff
10:10-12:00
   
Wed., 12/17
9:10-12:00
MA Exam and Practical (Lectures from 10/28-12/03 and All MA Lab material 9/22-12/11)


C. Histology Lab Instructors

Lab 1 (room 3051):  Dr. Tom McIntosh

Lab 2 (room 3052):  Dr. Mimi Jakoi 

Lab 3 (room 3053):  Dr. Joe Corless

Lab 4 (room 3054):  Dr. Steve Vigna

Lab 5 (room 3055):  Dr. Matt Velkey

Lab 6 (room 3056):  Dr. Jennifer Carbrey

D. Midterm and Final Exams

As shown on the schedule, there will be two Microscopic Anatomy exams.  Each exam will have a multiple choice portion as well as a practical exam portion.  The practical exam will ask you to examine, identify, and describe material on unknown VM slides.  Review Labs will be given before each exam, during which time your lab instructor will detail the format of each exam and provide you with the opportunity to hone your skills at examining VM sections.

 

 

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